What makes large epidemiological studies comparable?

What makes large epidemiological studies comparable?

R epeated cross-sectional surveys have been largely used to assess temporal trends in the prevalence of diseases. To be reliable, these should respect the following simple, but essential, rules: 1) the same source population should be randomly sampled and studied on different occasions, using the same sampling frame; 2) similar numbers of subjects should be selected; 3) the disease should be di...

Polymeric Gas Separation Membranes: What Makes them Industrially more Attractive?

What Makes

Parallel sequencing lives, or what makes large sequencing projects successful

T47D_rep2 and b1913e6c1_51720e9cf were 2 Hi-C samples. They were born and processed at the same time, yet their fates were very different. The life of b1913e6c1_51720e9cf was simple and fruitful, while that of T47D_rep2 was full of accidents and sorrow. At the heart of these differences lies the fact that b1913e6c1_51720e9cf was born under a lab culture of Documentation, Automation, Traceabilit...

Whole-Blood Gene Expression Profiles in Large-Scale Epidemiological Studies: What Do They Tell?

In nutrigenomics, gene expression profiling is used to investigate transcriptional mechanisms associated with nutrients and diet. Blood samples collected in the framework of dietary interventions and epidemiological studies allow the use of humans as the model system, as opposed to using cell lines or animal models. Here, we review recent publications in the field of gene expression profiling, ...